Contributing to TB elimination and health issues in Indonesia
Intervention areas
Local community partner
Direct beneficiaries (people with TB, PLHIV, and communities)
Yasa Karsa Insani (YKI), with Unitaid support through KNCV TB Foundation, implemented IMPAACT4TB to advance Indonesia’s adoption and evidence generation for short-course tuberculosis preventive therapy (3HP and 1HP). The project trained over 4,400 health workers, developed national guidelines, and conducted a clinical trial proving the regimens are safe and effective for national use.
Yasa Karsa Insani (YKI) implemented Mandiri TB with USAID support to strengthen community capacity and resource mobilisation for DR-TB care, establishing multi-sector forums, training patient groups for counselling and monitoring, and increasing treatment enrolment with 383 patients enrolled, 420 cadres trained, and five CSR initiatives launched.
Yasa Karsa Insani (YKI) implemented AMPUH with Global Fund support to enhance Indonesia’s HIV response by expanding viral load and early infant diagnosis testing. The project strengthened laboratory quality, integrated real-time specimen tracking with reporting systems, trained health workers, and improved testing coverage and turnaround time across 105 districts in 34 provinces.
Yasa Karsa Insani (YKI) with support from KOICA and the TB Alliance through KNCV TB Foundation, implemented LIFT-TB to accelerate adoption of shorter, safer drug-resistant TB treatments in 15 hospitals. The project strengthened clinical and laboratory capacity, supported operational research, and achieved a 97.6% treatment success rate, leading to Indonesia’s national adoption of the WHO-recommended BPaL/M regimen.
Yasa Karsa Insani (YKI), with Global Fund support, implemented AKSES VL to expand equitable access to HIV viral load testing across Indonesia. The project enhanced community engagement, trained over 9,000 participants, improved specimen tracking and laboratory quality, and increased testing coverage and efficiency nationwide.
Yasa Karsa Insani (YKI), supported by PT Agincourt Resources, implemented ENTAS TB in South Tapanuli to accelerate TB elimination through multi-sector collaboration, capacity building, and digital tools. The project established a Multi-sectoral Forum, developed a local TB action plan and regulation, and strengthened health worker and cadre skills.
Yasa Karsa Insani (YKI), as the local sponsor in collaboration with the Aurum Institute, with Unitaid support through KNCV TB Foundation, implemented the One To Three Study (2022–2025), a phase IV randomised clinical trial at Persahabatan Hospital comparing the safety, completion, and feasibility of 1HP and 3HP tuberculosis preventive regimens, confirming both as safe, effective, and suitable for programmatic use in Indonesia.
Yasa Karsa Insani (YKI), with support from the World Bank and Bill & Melinda Gates Foundation, implemented HARAPAN to strengthen private primary care providers’ capacity in TB financing and service delivery. The project enhanced case detection, data accuracy, provider collaboration, and increased treatment initiation in Bogor, Semarang, and Surabaya.